Study of Formulation and Evaluation of the Potential Inhibitory Power of Basil Leaf Extract Hand Sanitizer Gel (Ocimum Sanctum L.) Against Staphylococcus Aureus: Literature Review
DOI:
https://doi.org/10.38040/js.v14i2.481Abstract
Introduction: The basil plant (Ocimum sanctum) has the potential to be developed into antibacterial due to the content of tannin compounds, flavonoids, and essential oils. Antibacterial is a compound produced by microorganisms so that it can inhibit the growth of bacteria and kill bacteria that cause infection. The number of side effects so that many antibacterial developments are carried out derived from natural ingredients. The development of formulas for hand sanitizer gel preparations has been widely developed, including with various studies using various concentrations of basil leaf extract. This study was conducted to determine the gel formula for hand sanitizer ethanol extract of basil leaves (Ocinum Sanctum L.) which has the best inhibition against Staphylococcus bacteria.
Methods: Review literature is obtained from several journal libraries, journal searches, and trusted sites.
Results: There are 14 journals as a library, which display results from antibacterial gel preparation formulations, bacterial inhibitory testing and evaluation testing of basil leaves. The results of the review showed that basil leaves (Ocimum sanctum L.) have antibacterial activity against Staphylococcus aureus bacteria.
Conclusion: The best hand sanitizer gel formula was in a study conducted with a concentration of 8% basil leaf extract with an inhibitory power of 12.0 ± 3.10 mm which was included in the category of strong inhibitory power.
References
Amalia, A., Sari, I., & Nursanty, R. (2017). Aktivitas Antibakteri Ekstrak Etil Asetat Daun Sembung (Blumea balsamifera (L.) DC.) Terhadap Pertumbuhan Bakteri Methicillin Resistant Staphylococcus aureus (MRSA). Prosiding Seminar Nasional Biotik, 387–391.
Angelina, M., Turnip, M., & Khotimah, S. (2015). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Protobiont, 4(1), 184–189.
Atikah, N. (2013). Uji Aktivitas Antimikroba Ekstrak Herba Kemangi (Ocimum americanum L) terhadap Staphylococcus aureus dan Candida albicans. Universitas Islam Negeri Jakarta.
Brooks, G., Butel, J., & Morse, S. (2010). Mikrobiologi kedokteran. Jakarta: Salemba Medika.
Cahyani, N. M. E. (2014). Daun Kemangi (Ocinum Cannum) Sebagai Alternatif Pembuatan Handsanitizier. Jurnal Kesehatan Masyarakat, 9(2), 136–142.
Cushnie, T. P. T., & Lamb, A. J. (2005). Antimicrobial activity of flavonoids. Int J Antimicrob Agents, 26(5), 343–356. https://doi.org/10.1016/j.ijantimicag.2005.09.002
Dhale, D. A., & Pachkore, G. L. (2012). Phytochemicals, Vitamins And Minerals Content Of Three Ocimum Species. International Journal of Science Innovations and Discoveries, 2(1), 201–207.
Dorman, H. J. D., & Deans, S. G. (2000). Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J. Appl. Microbiol, 88, 308–316.
Farid, N., Nurhikma, A., Hamzah, S., Yusuf, M., & Rahmania. (2020). Aktivitas Antibakteri Hand Sanitizer Ekstrak Etanol Daun Kemangi (Ocimum Sanctum. L) Terhadap Escherichia coli dan Streptococcus Aureus. Media Kesehatan Politeknik Kesehatan Makassar, 15(2), 228–237. https://doi.org/10.32382/medkes.v15i2.1764
Febry, A., Yusriadi, A., & Tandah, M. R. (2015). Formulasi Sediaan Sabun Cair Antibakteri Minyak Atsiri Daun Kemangi (Ocimum americanum L.) dan Uji terhadap Bakteri Staphylococcus epidermidisdan Staphylococcus aureus. GALENIKA Journal of Pharmacy, 1(1), 1–8.
Ghafoor, D., Khan, Z., Khan, A., Ualiyeva, D., & Zaman, N. (2021). Excessive use of disinfectants against COVID-19 posing a potential threat to living beings. Current Research in Toxicology, 2, 159–168. https://doi.org/10.1016/j.crtox.2021.02.008
Herlina, N., Afiati, F., Cahyo, A. D., Herdiyani, P. D., Qurotunnada, & Tappa, B. (2017). Isolasi dan identifikasi Staphylococcus aureus dari susu mastitis subklinis di Tasikmalaya, Jawa Barat. Prosiding Seminar Nasional Masyarakat Biodiversitas Indonesia, 1(3), 413–417. https://doi.org/10.13057/psnmbi/m010305
Kadarohman, A. (2011). Komposisi kimia dan uji aktivitas antibakteri minyak kemangi (Ocimum americanum) terhadap bakteri Escherichia coli, shigella sonnei dan salmonella enteritidis. Berk Penel Hayat, 101–110.
Khalil, A. (2013). Antimicrobial Activity of Ethanolic Extracts of Ocimum basilicum leaf from Saudi Arabia. Biotechnology. https://doi.org/doi.org/10.3923/biotech.2013.61.64
Legowo, W. P., Warya, S., Damayanti, E., & Nurlitasari, N. (2020). Formulasi Dan Uji Antibakteri Gel Hand Sanitizer Yang Mengandung Minyak Atsiri Herba Kemangi (Ocimum americanum L.). Jurnal Sains Dan Teknologi Farmasi Indonesia Vol. IX, No. 2, Oktober 2020, IX(2), 23–33.
Maryunani, A. (2013). Perilaku Hidup Bersih dan Sehat (PHBS).
Nidha, A., Hadi, A., Farida, P., & Helmia. (2017). Efektivitas Minyak Atsiri Daun Kemangi (Ocimum Basilicum) Sebagai Antiseptik Untuk Higiene Tangan. Diponegoro University.
Novita, W. (2016). Uji Aktivitas Antibakteri Fraksi Daun Sirih (Piper Betle L) Terhadap Pertumbuhan Bakteri Streptococcus Mutans Secara In Vitro. Jambi Medical Journal, 4(2), 140 – 155.
Nurhasanah, & Gultom, E. S. (2020). Uji Aktivitas Antibakteri Ekstrak Metanol Daun Kirinyuh (Chromolaena odorata) Terhadap Bakteri MDR (Multi Drug Resistant) Dengan Metode Klt Bioautografi. Jurnal Biosains, 6(2), 45–52. https://doi.org/doi.org/10.24114/jbio.v6i2.16600
Rahmadani, A., Budiyono, & Suhartono. (2017). Gambaran Keberadaan Bakteri Staphylococcus Aureus, Kondisi Lingkungan Fisik, Dan Angka Lempeng Total Di Udara Ruang Rawat Inap Rsud Prof. Dr. M.A Hanafiah Sm Batusangkar. Jurnal Kesehatan Masyarakat (e-Journal), 5(5), 492–501.
Rohmani, S., & Kuncoro, M. A. A. (2019). Uji Stabilitas dan Aktivitas Gel Handsanitizer Ekstrak Daun Kemangi. Journal of Pharmaceutical Science and Clinical Research, 1, 16–28. https://doi.org/10.20961/jpscr.v4i1.27212
Turrohmah, N. A., & Shoviantari, F. (2021). Uji Aktivitas Antibakteri Gel Minyak Atsiri Daun Kemangi (Oscimum basillicum L) Terhadap Staphylococcus aureus. Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS), 2(02), 15. https://doi.org/10.30587/herclips.v2i02.2408
Wahyuningsih, S., Nugroho, H., Suhartono, S., Hadisaputro, S., & Adi, M. S. (2019). Faktor Risiko Kejadian Nefropati Diabetika pada Wanita. Jurnal Epidemiologi Kesehatan Komunitas, 4(1), 18. https://doi.org/10.14710/jekk.v4i1.4426
Zahra, H. D., Jamal, J., Jamal, S. M., & Mehdi, Z. (2015). Study Of The Effect Of Organic And Chemical Fertilizers On Qualitative And Quantitative Characteristics Of Lemon Basil (Ocimum Citriodorum Vis.). 4th National Congress on Medicinal Plants. Retrieved from https://www.sid.ir/paper/940521/en
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