The Description Neurotherapy in Ischemic Stroke Patients

Anisa Zulfa Fatihah


Introduction: Neuroprotectants are a therapy used to prevent the development of infarction in acute ischemic stroke patients. One approach to neuroprotective therapy is to start early administering neuroprotective agents to patients experiencing acute ischemic stroke. This study aims to describe the pattern of use of neuroprotectant drugs in ischemic stroke patients at RSUD Dr. Soegiri Lamongan.

Methods: This research method is a descriptive observational method with a cross-sectional study design. Data collection was carried out retrospectively by searching patient medical records and pharmaceutical installation data for the period June-December 2019.

Results: The majority of ischemic stroke patients were female (51.5%), the majority were aged 50-59 years (48.5%), had comorbid hypertension (79.4%) and comorbid DM and hypertension (20.6 %). The neuroprotective drug citicoline was prescribed in 32 patients (33%) and piracetam in 19 ischemic stroke patients (19.6%).

Conclusion: The highest use of neuroprotective drugs in ischemic stroke patients at RSUD Dr. Soegiri is a combination of citicoline and piracetam (44.3%%).

Full Text:



Alvarez-Sabín, J. et al. (2016) ‘Long-Term Treatment with Citicoline Prevents Cognitive Decline and Predicts a Better Quality of Life after a First Ischemic Stroke.’, International journal of molecular sciences. Switzerland, 17(3), p. 390. doi: 10.3390/ijms17030390.

Chen, S. et al. (2019) ‘The Conditions Under Which Piracetam Is Used and the Factors That Can Improve National Institute of Health Stroke Scale Score in Ischemic Stroke Patients and the Importance of Previously Unnoticed Factors From a Hospital-Based Observational Study in Taiwan’. doi: 10.3390/jcm8010122.

Dávalos, A. et al. (2012) ‘Citicoline in the treatment of acute ischaemic stroke: an international, randomised, multicentre, placebo-controlled study (ICTUS trial)’, The Lancet. Elsevier, 380(9839), pp. 349–357. doi: 10.1016/S0140-6736(12)60813-7.

Donmez, G. and Outeiro, T. F. (2013) ‘SIRT1 and SIRT2: emerging targets in neurodegeneration.’, EMBO molecular medicine. England, 5(3), pp. 344–352. doi: 10.1002/emmm.201302451.

Ebrahimi, S., Ashkani Esfahani, S. and Ebrahimi, A. (2022) ‘Comparison of the Effects of Citicoline and Piracetam on Hypoxic-ischemic Brain Damage in Neonatal Rabbits.’, Iranian journal of child neurology. Iran, 16(1), pp. 77–84. doi: 10.22037/ijcn.v15i4.29816.



  • There are currently no refbacks.

Copyright (c) 2023 Surya : Jurnal Media Komunikasi Ilmu Kesehatan

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Faculty of Health Sciences, Universitas Muhammadiyah Lamongan

Jl. Raya Plalangan-Plosowahyu Km. 3 Kabupaten Lamongan Jawa Timur, Kode Pos 62218


Journal Surya is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License. © All rights reserved 2017. Journal Surya p-ISSN 1979-9128 ISSN Online 2715-064X

Indexing and Database